PCI ECOS-CONICYT (C16S01). Abeta assemblies propagation and cell damage. 2017-2019
Co-investigador.

FONDECYT 1201496. Deciphering the role of mitochondrial vitamin C in neurodegenerative diseases. 2020-2024. Co-investigador
VRID (2019.033.111-INV) 2017-2019
Co-investigador

EXPLORA (ED230153). Las señas de mi Tierra. Asesor Científico.

• Moraga-Cid G, San Martín VP, Lara CO, Muñoz B, Marileo AM, Sazo A, Muñoz-Montesino C, Fuentealba J, Castro PA, Guzmán JL, Burgos CF, Zeilhofer HU, Aguayo LG, Corringer PJ and GE Yévenes. Modulation of glycine receptor single-channel conductance by intracellular phosphorylation. Sci Rep. 10(1):4804. doi: 10.1038/s41598-020-61677-w.

• Roa FJ, Peña E, Gatica M, Escobar-Acuña K, Saavedra P, Maldonado M, Cuevas ME, Moraga-Cid G, Rivas CI, Muñoz-Montesino C. 2020. Therapeutic Use of Vitamin C in Cancer: Physiological Considerations. Front Pharmacol. 11:211. doi: 10.3389/fphar.2020.00211.

• Roa FJ, Peña E, Inostroza E, Sotomayor K, González M, Gutierrez-Castro FA, Maurin M, Sweet K, Labrousse C, Gatica M, Aylwin CF, Mendoza P, Maldonado M, Delgado C, Madariaga J, Panes J, Silva-Grecchi T, Concha II, Moraga-Cid G, Reyes AM, Muñoz-Montesino C, Vera JC, Rivas CI. 2019. Data on SVCT2 transporter expression and localization in cancer cell lines and tissues. Data in Brief. 25:103972. doi: 10.1016/j.dib.2019.103972.

• Peña E, Roa FJ, Inostroza E, Sotomayor K, González M, Gutierrez-Castro FA, Maurin M, Sweet K, Labrousse C, Gatica M, Aylwin CF, Mendoza P, Maldonado M, Delgado C, Madariaga J, Panes J, Silva-Grecchi T, Concha II, Moraga-Cid G, Reyes AM, Muñoz-Montesino C*, Vera JC, Rivas CI*. 2019. Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer. Free Radic Biol Med 135:283-292. * Corresponding authors.

• Lara Lara CO, Burgos CF, Silva-Grecchi T, Muñoz-Montesino C, Aguayo LG, Fuentealba J, Castro PA, Guzmán JL, Corringer PJ, Yévenes GE, Moraga-Cid G. 2019. Large Intracellular Domain-Dependent Effects of Positive Allosteric Modulators on Glycine Receptors. ACS Chem Neurosci doi: 10.1021/acschemneuro.9b00050.

• Maldonado M, Inoztroza E, Peña E, Moncada N, Mardones L, Medina JL, Muñoz A, Gatica M, Villagrán M, Escobar E, Mendoza P, Roa FJ, Gonzalez M, Guzman P, Gutierrez-Castro FA, Sweet K, Munoz-Montesino C, Vera JC, Rivas CI. Sustained blockade of ascorbic acid transport asociated with marked SVCT1 loss in rat hepatocytes containing increased ascorbic acid levels alter parcial hepatectomy. Free Radical Biol Med. 108:655-667.

• Muñoz-Montesino C, Sizun C, Moudjou M, Herzog L, Reine F, Igel-Egalon A, Barbereau C, Chapuis J, Ciric D, Laude H, Béringue V, Rezaei H, Dron M. 2017. A stretch of residues within the protease-resistant core is not necessary for prion structure and infectivity. Prion 11:1-6

• Muñoz-Montesino C, Sizun C, Moudjou M, Herzog L, Reine F, Chapuis J, Ciric D, Igel-Egalon A, Laude H, Béringue V, Rezaei H, Dron M. 2016. Generating mammalian prions with internal deletions. J Virol. 90:6963-75

• Muñoz-Montesino, C, Roa FJ, Peña E, González M, Sotomayor K, Inostroza E, Muñoz CA, González I, Maldonado M, Soliz C, Reyes AM, Vera JC, Rivas CI. 2014. Mitochondrial ascorbic acid transport is mediated by a low-affinity form of the sodium-coupled ascorbic acid transporter-2. Free Radic Biol Med 70:241-254.

• Salamat MK, Munoz-Montesino C, Moudjou M, Rezaei H, Laude H, Béringue V, Dron M. 2013. Mammalian prions: tolerance to sequence changes-how far? Prion 7:131-135.

• Montecinos V, Guzmán P, Barra V, Villagrán M, Muñoz-Montesino C, Godoy A, Sotomayor P, Sotomayor K, Escobar E, Guzmán C, Vásquez O, Bustamante M, Rivas C, Vera JC. 2007. Vitamin C is an Essential Antioxidant that enhances Survival of Oxidatively Stressed Human Vascular Endothelial Cells in the presence of a Vast Molar Excess of Glutathione. J. Biol. Chem. 282:15506-15515.

• Muñoz Montesino C, Andrews E, Moraga-Cid G, Rivers R, Gonzalez Smith A, Folch H, Cespedes, Oñate A. 2004. Intraspleen delivery of a DNA vaccine coding for superoxide dismutase (SOD) of Brucella abortus induces SOD-specific CD4+ and CD8+ T cells. Infection and Immunity 72:2081-2087.

• Oñate A, Cespedes S, Cabrera A, Rivers R, Gonzalez A, Muñoz, C, Folch H, Andrews E. 2003. A DNA vaccine encoding Cu/Zn superoxide dismutase of Brucella abortus induces protective immunity in BALB/c mice. Infection and Immunity 71: 4857-4861.

Laboratorio de Neuropatología Molecular

Equipo de Trabajo:

• Kathleen Escobar Acuña (alumna de Magister en Neurobiología)
• Paulina Saavedra Sieyes (alumna de Magister en Neurobiología)

Talleres a la comunidad: Impacto Clinico y Social de la Neurociencia. 13 de Septiembre, 2018. Universidad de Concepcion and FEN. Organizadora

Organización de Cursos: International Postgraduate Course: “Insights into comprehensive neuroscience: Understanding brain function and pathology from an interdisciplinary point of view”. Universidad de Concepcion, Chile. September 6-12, 2018. Organizadora

Organización de Cursos: International Postgraduate Course: “Neurodegeneration: Insights in molecular mechanisms and therapies” Universidad de Concepcion, Chile. July 5-7, 2017. Organizadora

Charlas en Biblioteca Municipal, Liceo de Niñas, Colegio Concepción, Colegio Madre Paulina.