Arriagada, V., Osorio, A., Carrera-Naipil, C., Villacis-Aguirre, C. A., Escobar, C., Morales, N., … & Oñate, Á. A. (2025). In Silico Design and Characterization of a Multiepitope Vaccine Candidate Against Brucella canis Using a Reverse Vaccinology Approach. Journal of Immunology Research, 2025(1), 6348238. Doi: 10.1155/jimr/6348238
Flores-Concha, M., Gómez, L. A., Soto-Shara, R., Molina, R. E., Coloma-Rivero, R. F., Montero, D. A., … & Oñate, Á. (2024). Brucella abortus triggers the differential expression of immunomodulatory lncRNAs in infected murine macrophages. Frontiers in Immunology, 15, 1352306. Doi: 10.3389/fimmu.2024.1352306
Molina, R. E., Osorio, A., Flores-Concha, M. R., Gómez, L. A., Ferrari H, Í., & Oñate, A. A. Immunoinformatic design of a multivalent vaccine against Brucella abortus and its evaluation in a murine model using a DNA primeprotein boost strategy. Frontiers in Immunology, 15, 1456078. Doi: 10.3389/fimmu.2024.1456078
Valdebenito-Navarrete, H., Fuentes-Barrera, V., Smith, C. T., Salas-Burgos, A., Zuniga, F. A., Gomez, L. A., & García-Cancino, A. (2023). Can Probiotics, Particularly Limosilactobacillus fermentum UCO-979C and Lacticaseibacillus rhamnosus UCO-25A, Be Preventive Alternatives against SARS-CoV-2?. Biology, 12(3), 384. Doi: 10.3390/biology12030384
Montero, D. A., Vidal, R. M., Velasco, J., George, S., Lucero, Y., Gómez, L. A., … & O’Ryan, M. (2023). Vibrio cholerae, classification, pathogenesis, immune response, and trends in vaccine development. Frontiers in Medicine, 10, 1155751. Doi: 10.3389/fmed.2023.1155751
Montero, D. A., Garcia-Betancourt, R., Vidal, R. M., Velasco, J., Palacios, P. A., Schneider, D., … & Carreño, L. J. (2023). A chimeric protein-based vaccine elicits a strong IgG antibody response and confers partial protection against Shiga toxin-producing Escherichia coli in mice. Frontiers in Immunology, 14, 1186368. Doi: 10.3389/fimmu.2023.1186368
Gómez, L. A., Molina, R. E., Soto, R. I., Flores, M. R., Coloma-Rivero, R. F., Montero, D. A., & Oñate, Á. A. (2023). Unraveling the Role of the Zinc-Dependent Metalloproteinase/HTH-Xre Toxin/Antitoxin (TA) System of Brucella abortus in the Oxidative Stress Response: Insights into the Stress Response and Virulence. Toxins, 15(9), 536. Doi: 10.3390/toxins15090536
Coloma-Rivero RF, Gómez L, Alvarez F, Saitz W, del Canto F, Céspedes S, Vidal R and Oñate AA (2020) The Role of the Flagellar Protein FlgJ in the Virulence of Brucella abortus. Frontiers in Cellular Infection Microbiology, 10,178. Doi: 10.3389/fcimb.2020.00178
Gómez, L. A., Alvarez, F. I., Molina, R. E., Soto-Shara, R., Daza-Castro, C., Flores, M. R., … & Oñate, A. A. (2020). A Zinc-Dependent Metalloproteinase of Brucella abortus Is Required in the Intracellular Adaptation of Macrophages. Frontiers in Microbiology, 11, 1586. Doi: 10.3389/fmicb.2020.01586
León, Y., Zapata, L., Molina, R. E., Okanovic, G., Gómez, L. A., Daza-Castro, C., … & Oñate, A. A. (2020). Intranasal Immunization of Mice with Multiepitope Chimeric Vaccine Candidate Based on Conserved Autotransporters SigA, Pic and Sap, Confers Protection against Shigella flexneri. Vaccines, 8(4), 563. Doi: 10.3390/vaccines8040563
Gómez, L.A. & Oñate, A. A. (2019). Plasmid-Based DNA Vaccines. In Munazza Gull (ed.), Plasmid ( 1st. ed., pp. 1-14). London, IntechOpen. Doi: 10.5772/intechopen.76754
Gómez, L., Alvarez, F., Betancur, D., & Oñate, A. (2018). Brucellosis vaccines based on the open reading frames from genomic island 3 of Brucella abortus. Vaccine, 36(21), 2928-2936. doi: 10.1016/j.vaccine.2018.04.014
Gómez, L., Llanos, J., Escalona, E., Sáez, D., Álvarez, F., Molina, R., … & Oñate, A. (2017). Multivalent Fusion DNA Vaccine against Brucella abortus. BioMed Research International, 2017, Article ID 6535479. doi: 10.1155/2017/6535479
Gómez, L.A., Alvarez, F.I., Fernández, P.A., Flores, M.R., Molina, R.E., Coloma, R.F. y A.A. Oñate, «Immunogenicity and Protective Response Induced by Recombinant Plasmids Based on the BAB1_0267 and BAB1_0270 Open Reading Frames of Brucella abortus 2308 in BALB/c Mice», Frontiers in Cellular and Infection Microbiology 6(117), 1-6 (2016)
Gómez, L. A., Cortes, R. A., & Smith, C. T. (2015). Efecto in vitro del levamisol sobre las celulas mononucleares de la sangre periférica de trucha arcoíris (Oncorhynchus mykiss). Gayana (Concepción), 79(2), 161-166. doi: 10.4067/S0717-65382015000200006
Gómez, L., Cortés, R. y C. Smith, «Effect of PHA and LPS on the activity of nonspecific Cytotoxic cells and macrophages of rainbow trout (Oncorhynchus mykiss)», Gayana, 77(1), 53-59 (2013).
Gómez, L., Cortés, R., Valenzuela, A. y C. Smith, «Kinetics of reactive oxygen species produced by rainbow trout (Oncorhynchus mykiss) leukocytes and the effect of the antioxidant astaxanthin», Acta veterinaria BRNO 82(4), 435-439 (2013).
El Dr. Oyarzun es investigador adjunto del Laboratorio de Parasitología del Departamento de Microbiología de la Facultad de Ciencias Biológicas de la Universidad de Concepción.
